The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology


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The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease.

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The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin.


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The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces faecal microbiota transplantation , and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position.

Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis.


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Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity - periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major 'idiopathic' diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity.


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The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology
The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology

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